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Retatrutide achieved up to 24.2% body weight reduction in 48 weeks in Phase 2, and the recently completed Phase 3 TRIUMPH-4 trial pushed that number to an unprecedented 28.7% at 68 weeks

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In this study, we find that the GSH-deficient mutant, in spite of the highly accumulated Glu previously defined as a critical wound signal essential for activating plant defense events, showed impaired plant defense signaling events (Fig